For Research Purposes Only · Not For Human Consumption
Anti-Inflammatory Research
C-terminal α-MSH tripeptide (Lys-Pro-Val). Researched for NF-κB suppression, gut inflammation and mast-cell modulation.
£24.99
In stockInc. VAT · Add £25.01 more for free UK shipping
SSL encrypted · Same-day dispatch before 6pm · CoA on this lot
Independently HPLC-tested. Lot-matched CoA available on request — quote your batch and order ID.
What ships with your order
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of α-melanocyte stimulating hormone (α-MSH), retaining significant anti-inflammatory activity of the parent peptide while lacking pigmentary effects. Published research has documented NF-κB pathway suppression, mast-cell stabilisation and protective effects in models of inflammatory bowel disease and skin inflammation. ≥98% HPLC, third-party CoA.
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of α-melanocyte stimulating hormone (α-MSH), retaining significant anti-inflammatory activity of the parent peptide while lacking pigmentary effects. Extensively researched for NF-κB suppression, mast-cell stabilisation and protective effects in inflammatory bowel disease and skin inflammation models. Peptides UK supplies KPV 10mg as ≥98% HPLC lyophilised powder with a signed third-party Certificate of Analysis.
KPV consists of just three amino acids — lysine, proline and valine — corresponding to residues 11-13 of α-MSH. Despite its small size, KPV retains a substantial fraction of α-MSH's anti-inflammatory activity in multiple research models while being pharmacokinetically simpler, more stable, and free of melanocortin receptor pigmentary effects. It is one of the smallest bioactive peptides in the current research literature.
Published research has documented KPV suppression of NF-κB activation in immune cells, inhibition of pro-inflammatory cytokine release (TNF-α, IL-6, IL-8), mast-cell stabilisation reducing histamine release, and protective effects on epithelial barrier integrity in gut and skin models. Its mechanism appears to be substantially receptor-independent — cytoplasmic uptake and direct interference with inflammatory transcription factor activation is one leading hypothesis in the literature.
Published research has investigated KPV in inflammatory bowel disease (Crohn's and ulcerative colitis) models, atopic dermatitis and psoriasis research, mast-cell and allergy pathway studies, epithelial barrier integrity research, wound-healing inflammatory-phase studies, and comparative anti-inflammatory pharmacology against BPC-157 and other repair peptides. The 10mg vial supports extended research protocols.
Store the lyophilised vial at -20°C, sealed and protected from light. Reconstitute with bacteriostatic water (0.9% benzyl alcohol) — typically 1–2ml per 10mg vial. Add solvent slowly down the side of the vial; do not shake. Refrigerate the reconstituted solution at 2–8°C and use within 28 days. Do not refreeze after reconstitution.
Every KPV 10mg lot is independently HPLC-UV tested to ≥98% purity by Janoshik Analytical or Aspen Bioanalytics, with mass-spectrometry identity confirmation against the published molecular weight of 342.44 Da. The signed PDF Certificate of Analysis is supplied with every order and matches the vial lot number.
UK-stocked, same-day Manchester dispatch, third-party HPLC verification on every batch and Royal Mail Tracked 24 with insulated cold-chain packaging. Full lot traceability from vial sticker to signed CoA visible on this page.
Related search terms
KPV is the C-terminal tripeptide (Lys-Pro-Val) of α-melanocyte-stimulating hormone (α-MSH). It retains a substantial fraction of α-MSH's documented anti-inflammatory activity in cell and animal models while lacking the pigmentary activity mediated by the full peptide's binding to MC1R.
Regulatory & compliance notice
This product is supplied strictly for in-vitro laboratory research. It is not a licensed medicine in the United Kingdom, is not approved by the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency for human or veterinary use, and is not intended to diagnose, treat, cure or prevent any disease. Nothing on this page constitutes medical advice.
External links point to primary literature or regulatory records and open in a new tab. Citations are provided so the reader can independently verify every factual claim made on this page. Last reviewed 22 July 2026.
Certificate of Analysis
KPV 10mg
The CoA you download is the exact certificate produced for this lot — no edits.
Storage & handling
Keep it stable, keep it sterile
Recovery / Healing
BPC-157 · 5mgBody Protection Compound-157. Widely researched for tissue repair, gut health and joint recovery.
£15.99
Skin / Anti-Ageing Blend
KLOW · 80mgHigh-payload copper peptide + repair blend. KPV + GHK-Cu + BPC-157 + TB-500 co-lyophilised for advanced collagen and connective-tissue research.
£69.99
Accessories / Reconstitution
Bacteriostatic Water · 3ml0.9% benzyl alcohol bacteriostatic water for peptide reconstitution. Pharmaceutical-grade, sterile-filtered 3ml vial.
£4.99
Every batch independently tested by Janoshik Analytical and Aspen Bioanalytics before dispatch. Signed certificates available on every product page.
Legal notice
This product is sold strictly for in-vitro laboratory research purposes only. It is not approved for human or veterinary use, is not a drug, food, or cosmetic, and should not be misused as such. Peptides UK accepts no liability for misuse. By purchasing you confirm you are a qualified researcher aged 18 or over.
KPV 10mg
£24.99