Buy TB-500 5mg UK | Research Grade

TB-500 is a synthetic peptide corresponding to the active region of Thymosin Beta-4, a 43-amino-acid naturally occurring peptide present in nearly all human tissues and the highest-concentration G-actin sequestering molecule in mammalian cells. Synthetic TB-500 reproduces the biologically active fragment responsible for actin regulation, cell migration and angiogenesis observed in TB4 research, while being significantly more soluble and easier to handle in laboratory settings.

Research has linked TB-500 to G-actin sequestration and cytoskeletal reorganisation, upregulation of cell migration in fibroblasts, keratinocytes and endothelial cells, modulation of inflammation through suppression of NF-κB signalling, promotion of angiogenesis via VEGF and tie-2 pathways, and accelerated tissue repair in cardiac, dermal and musculoskeletal models. Its small size relative to native TB4 also gives it favourable distribution properties in tissue-penetration research.

Published research has investigated TB-500 in wound-healing models, cardiac ischaemia and post-infarction repair studies, corneal regeneration, tendon and ligament recovery, neuroprotection in stroke models, hair follicle migration studies, and inflammation modulation in autoimmune research models. It is widely used alongside BPC-157 in comparative recovery-peptide research because the two compounds act through different but complementary regenerative pathways.

Store the lyophilised TB-500 vial at -20°C, sealed and protected from light. Reconstitute with bacteriostatic water (0.9% benzyl alcohol) — a typical starting volume is 2ml per 5mg vial. Add solvent down the inside wall of the vial gently; do not agitate. Once reconstituted, refrigerate at 2–8°C and use within 28 days. Do not refreeze after reconstitution.

Every TB-500 5mg vial is independently tested by Janoshik Analytical or Aspen Bioanalytics to ≥98% HPLC-UV purity with mass-spectrometry identity confirmation against the published molecular weight of approximately 4,963 Da. The signed PDF Certificate of Analysis is supplied with every order and matches the lot number printed on the vial.

Peptides UK is a UK-based research peptide supplier with same-day dispatch on orders before 6pm GMT, cold-chain insulated packaging, Royal Mail Tracked 24 delivery, and verifiable third-party batch CoAs available on request. Stocked in the UK, dispatched from Manchester, supported by a UK customer service team that replies within 4 working hours.