Buy MT-2 10mg UK | Research Grade

Melanotan II is a synthetic cyclic analogue of α-MSH developed at the University of Arizona in the 1980s as a more stable, longer-acting research tool for studying the melanocortin receptor system. The peptide acts as a non-selective agonist at MC1R, MC3R, MC4R and MC5R receptors, making it one of the most useful reference compounds for exploring the entire melanocortin signalling network in cell-based and animal-model research.

MC1R agonism drives melanogenesis in melanocytes through cAMP-mediated upregulation of tyrosinase and downstream eumelanin synthesis — the basis of MT-2's well-documented pigmentation effects in research models. MC4R agonism is implicated in central appetite regulation and sexual function research, while MC3R and MC5R agonism are studied in inflammatory and exocrine pathway research. The cyclic structure of MT-2 confers metabolic stability significantly greater than native α-MSH, enabling longer-duration research protocols.

Published research has investigated MT-2 in melanogenesis and pigmentation studies, MC1R/MC3R/MC4R/MC5R receptor pharmacology, appetite and energy-balance research, libido and sexual function pathway studies, photoprotection and UV-response research, and inflammation modulation in MC receptor knockout models. The 10mg vial supports typical research-scale protocols with sufficient material for multi-week experiments at standard reconstitution concentrations.

Store the lyophilised vial at -20°C, sealed and protected from light. Reconstitute with bacteriostatic water (0.9% benzyl alcohol) — typically 1ml or 2ml per 10mg vial. Add solvent down the inside wall of the vial slowly; do not shake. Refrigerate the reconstituted solution at 2–8°C and use within 28 days. Do not refreeze.

Every MT-2 10mg vial is independently tested by Janoshik Analytical or Aspen Bioanalytics to ≥98% HPLC-UV purity with mass-spectrometry identity confirmation against the published molecular weight of 1,024.18 Da. The signed PDF CoA is supplied with every order and matches the vial lot number.

Melanotan II is one of the longest-established research peptides on the grey market, which means counterfeit and under-dosed product is unusually widespread. Peptides UK counters this with mandatory third-party HPLC verification on every batch, UK-stocked inventory, same-day Manchester dispatch and full lot traceability — visible directly on this product page.